Sputtering in drive: 2001 Ford Ranger V6 3.0 Automatic Transmission

I recently acquired a 2001 Ford Ranger and put a 3.0 V6 Engine (not transmission) from a 2006 Ranger in it. Once everything was plugged up, i replaced the air filter, fuel pump, coil pack, plugs, plug wires, battery, fuel, transmission fluid, oil filter, and oil. The truck starts up and idles perfectly, the only issue is when it’s put in drive it sputters and hesitates to drive. Brought it to a mechanic who read 4 codes for O2 Sensors and codes for literally every solenoid. He jacked it up and attempted to see if it was struggling to shift into first and it was, but when in second it accelerates perfectly. I decided to change every solenoid (i had new ones already so why not) and now the truck only idles and goes in reverse, no drive function at all. I was also told to change the CKP sensor to the original 2001 one and this did not solve the issue. Any advice would help, i believe maybe the wiring to my transmission may be pushing low voltage or possibly something with the valve body?

Were they both the same type 3.0 ?, Ford had 2 different 3.0’s in the Ranger, Flex Fuel vs Reg Fuel.

For the engine itself, the fuel injectors need to remain the same type as what the truck came with.

First thing I would look for is a pinched wiring harness. Then make sure the ground connections are all installed back properly. Verify power at the transmission itself…

What year throttle body/TPS did you use, the 01 or 06??

The TPS seems to be different between the 2 years, since both years have electronically controlled transmissions, but one is a 4 speed and the other a 5 speed, the years need to match or the ECM/TCM could be receiving false information…

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My first thought upon reading that the OP “mated” a 2006 Ford engine to a 2001 Ford transmission was that the ECM and TCM can’t communicate properly with each other.