I have a 2002 Honda CRV-LX with over 200,000 miles. I’m experiencing a loud hum and vibration between 40 and 50 mph on acceleration and deceleration. It occurs when I’m driving straight or turning left, but goes away when I turn right.
You probably need a new wheel bearing on your passenger’s side. Whether front or rear you might have a guess but will probably have to wait for inspection. If the bearings are the same age its probably a good idea to just have both sides done - when one goes the other is often not far behind.
Do not wait. A bad wheel bearing is bad.