I have a 2014 Toyota Highlander XLE with the same problem all 4 door actuators went out at the same time. Toyota told me parts and labor would cost me $1,990.00 to repair all four doors back to operating.
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It would be very unusual for all 4 actuators to fail at the same time. I would seek a second opinion.
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All 4 actuators in a week went bad. Toyota told me that they are aware of the problem but have never issue a recall.
I assume you mean the door lock actuators? If all four died at the same time, my first suspicion would be the driver’s side switch panel.
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All the door locks are controlled by the body control module.
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It’s a six year old vehicle, things wear out.