Go with OEM or aftermarket turn signal/headlight/wiper switch on Ford truck?

Probably would be a good idea, especially since you’ve got that odd light duty F250 with 150 and 250 parts, if I recall correctly. Some of those terminals may be for cruise control equipped vs not. Would be true for GM, anyway. I don’t remember Ford’s cruise control switches exactly. They might just be on the steering wheel, so might not apply.