Acura dies

On three different occasions at least one week separating each my 1999 Acura 3.2TL has died during operation. Once at 25mph, once at 40mph, and once on the interstate (on cruise control) at 70mph. Each time I went to neutral, restarted and drove on. What would cause this?

Dirty fuel filter, etc., etc., etc., etc.
Possibly a problem developing in the spark generating components.

Ignition switch is a possibility.