As I stated earlier, I have not experienced any tire problems with my 2006 Chevrolet Uplander that has gone the same number of miles that yours has. I did check my tires and they are Goodyear Integra–P225R60 by 17. Your problem may be due to the tread pattern, although if you have the same kind of tires that I have, I should be experiencing the same difficulty. I did have the intermediate steering shaft replaced under warranty which my dealer indicated was an issue with the Chevrolet Uplanders. However, I don’t see where this would cause a tire problem. The intermediate steering shaft caused sort of a bumpy feeling in the steering wheel. The institution where I am employed has Chevrolet Uplanders in the fleet. If I get a chance, I’ll ask the mechanics at our motor pool if these minivans have had tire problems.