2003 GMC Sierra 1500 Engine Shudder/Vibration

Since bought new, this vehicle has an engine shudder/vibration that occurs routinely at about 42mph thru 45mph. Also, with light pedal pressure from a stop, around corners and while going slow thru parking lots. More noticeable during cold weather. Any ideas?

Do you mean it happens at about 45 mph and while driving slow (and straight?) in a parking lot and while turning (at what speeds?) ?

Could it be described as a "clicking?"

I’m going to suggest a loose or possibly cracked vacuum hose or other air intake (loose plenum bolt).