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Vibrations in 2006 Saturn Vue

What would cause a vibration to occur in a 2006 Saturn Vue @ 45 MPH?

Helping to narrow down when and why it happens could help. Most common for general vibration at that speed would be wheel balance or alignment. If it happens only when you put on the brakes, the rotors. The more info, the better the guess, the best guess can be made by a qualified service individual who can analyze the problem and recommend the proper repair.

Thanks. Just had brakes and rotors replaced; the vibration goes off immediately when traveling less than 45 mph. Smooth as silk under 45 mph. ???

Does the sound vary while turning the steering wheel at that speed? If so wheel bearings.