Problems with 93 Probe

Help! have a 93 probe with 186,00 miles.Fate has brought it to me with some issues-she spits and sputters.We have tried replacing plugs,wires,fuel injector cleaner-each time it seems to run worse than before.Any suggestions?

spits and sputters

How about a little more detail. When how much etc.

all the time-at start up, if you give it too much gas,idiling it was smoothing out after it shifted into second gear but since plugs were changed it doesn’t at all