2002 Chevrolet Avalanche - radio won’t work after rear end change

I had to change the rear end and now the Radio will not come on and the battery runs down every night,i checked the fuse is good for radio

The only thing I can think of this might be related to the ABS system when the rear end was swapped out. Or does your rear ended have an e-locker? That might be a problem source.
Neither however should affect the radio, just the battery drain.
The radio failure could just be a coincidence.