I just replaced Latitude Tour tires on my 2013 Equinox at 6/32" front and 4/32" back tread. Nicest OEM tires I've ever had, but I wanted a little more rain and snow traction. The local BJs had Latitude, LTX Defender, and the Premier LTX tires at a reasonable price.
I went with the LTX Defender since I do some driving on dirt roads and the mileage rating (70k) was higher than the other choices. I was concerned the tires might be louder and have a harsher ride than the Latitude. The Defenders are quiet and have a smooth ride despite the more aggressive tread. There is a drop in mpg (3-5%) but rain traction is much better. Overall, I'm satisfied with my choice.
Probably can't go wrong with any of these tires.