Runs rough

1996 s-10 runs very rough at start-up…smooths out after it warms up and runs really great. Is it just the plugs and wires or something else??

How many miles does it have on it?
Has the maintenance been kept up to date?
Have you had a Check Engine Light?

It may be just the plugs and wires, but it could also be something else. It’s possible, for example, that the temp sensor is giving an erroneous signal and the ECU thinks the engine is warmer than it actually is.

Plugs and wires are easy to chang, and of they haven’t been done in a long time I’d start there…and change the rotor, distributor cap, and air filter while I had the hood up.