Has anyone had any problems with the 2018 Ford F250 Crew Cab 4x4 Diesel
Are you having one? If you are, I would recommend taking it back to the dealer since you are under warranty
Doug, In order to make an intelligent, informed response to this query, more information is needed.
Are you considering buying one?
Do you own one?
Are you experiencing a problem with one?
If “yes,” specifically what problem?
CSA 
Given the large numbers of them sold, it is a certainty that some people have had problems.
Maybe. It depends.