Mass Air Flow Sensor or Cylinder misfire

2001 Olds Alero. i’m getting a P0300 reading, Cylinder misfire, and i was told a coupld months ago my mass air flow sensor was out of range. are they related? how serious is a misfire? can i drive a couple hundred miles before service? advice and education welcome

Could be bad plugs, vacuum leak, low fuel pressure, bad battery, dirty battery connections… Watch this video and it could help.

P0300 is multiple cylinder random missfire. I would not drive that long on a missfire the unburned fuel can destroy your catalytic converter. I would start off checking the ignition coils and module. If memory serves me correctly the coils were mounted to a module and both were prone to failure.