Frankly I think you are making this way too difficult . But my thoughts are: why be hung up on used luxury vehicles, I would never buy a used all wheel drive vehicle or a used hybrid and the same as before-just find something you like and have a mechanical inspection and drive on.
The above paragraph proves forum answers will have personal bias.
I disagree about how an IS would be driven. Itās handling is poor when compared to other sports sedans of that time period. If someone wanted to push the limits of a small sports sedan, they probably would have bought an Audi or BMW.
The Lexus IS AWD has a hump in the driverās side floor that helps make the car feel cramped inside compared to the german rivals (and most compare it to the BMW 3 Series and the Audi A4) It has been reliable but CR didnāt have enough data on the 2009 (2010 and Later)
The Prius V has more cargo room than the original Prius but at the expense of gas mileage (friends have owned both) My parents have had a Prius for coming on 8yrs now with no issues. My dad is looking at the Hybrid RAV4 for himself now that heās seen the benefits of the Hybrid System.
The Rav4 Hybrid just came out this year but is basically the Camry Hybrid in RAv4 form. Should be just as reliable based on friends/neighbors experience with the camry hybrid. Dad is looking to buy something with more safety/comfort features than his 10yr old CRV and the hybrid makes sense to him.