Roughly 2 hours into a long trip on a very hot day, our 2009 Honda Accord air conditioning will go from blowing nice cold air to just blowing not at all cool air. Normally the air is cranked to the coldest setting and not blowing on full blast. Both times we have stopped and left the car off for about 30 minutes and come back and all is well (cold air blows again).
Have you tried just turning off the a/c but leaving the fan blowing? If it clears up after a while it could be your evaporator is icing up, possibly caused by a slow condensation drain.
Also try using a higher blower speed and tempering the air> the same thing happened with our house AC because when we had the blower replaced it was replaced with one that didn’t have enough CFM capacity.
It is possible the freon is overcharged, and the system is shutting itself off to prevent compressor failure. Also make sure your condenser is nice and clean and not full of dead bugs.