For a v6 suv awd or 2 wheel

I want to buy a 2011 jeep Cherokee
What is safer to drive Awry or rear quell drive?

correctione Awd or rear wheel drive

It always depends upon the conditions.

I can think of no cases where rwd would be safer than awd, and I can think of cases where awd would be safer than rwd (slippery conditions).

One benefit I have seen in some trucks is better load carrying handling and capacity of rwd over their awd/4wd counterparts. The opposite is true if awd is compared to fwd in other vehicles.