Yes it's possible.
The Ford diesels use a HUII type injector instead of a Bosch type. They are electronically and high pressure oil driven. There's a high pressure oil pump on the back of the engine that provided the hydraulic power to drive the injector and an electric solenoid on top of each injector that releases it. Inside each head are 2 sets of cavities. One for oil and one for fuel. The electric fuel pumps put the fuel into the heads and pressurize it and both fuel and oil go into their respective cavities in the injectors. When the solenoid fires, it releases the injector and the oil pressure forces fuel into the cylinder.
Of course the heads are on top of the block with a head gasket between them and the water jacket of the engine with the coolant in it.
The 7.3L Powerstrokes were relatively bullet proof save the electrical gizmo called a cam shaft position sensor that nearly every owner carries a spare around with them. With the 6 liter, for reduced the engine size by nearly 100 cubic inches and increased the horsepower by about 75 horses. The 6.0 is a modified VT365 Navistar which is not really a bad engine however, in the Navistar form it's about 230 horse power. In the Ford form it's 350 or so horse power. To do this, Ford used a lot larger turbo charger than they had previously. The boost on an old 7.3 engine is about 11 or 12 pounds. It's over 30 on the 6.0 liter. That little engine can't take that kind of pressure.
One of the root causes of the problems with this piece of crap is the EGR system which they never did figure out until they put a particulate filter on it for the new 6.4 engine. The EGR feeds exhaust back to be reburned. The sooty diesel exhaust drops soot in the intake which eventually collects on another stupid Ford idea, the Variable Vaned Turbo. The turbo on the 6.0 liter has vanes that open and close like an airplane propeller to adjust the amount of boost. Otherwise at higher RPM's you'd end up sticking 50 psi of boost into the engine and blowing thing up. The problem is, that soot gets into the pivots of the vanes and eventually they get stuck. If they stick in the closed highway position, you can't get the truck to pull out from a dead stop. It'll have 0 low end power. If it sticks in the high boost position, it will blow things apart on the engine like the boost tubes if you are lucky. If you are unlucky, it may be the manifold cooler, or worst case, lift the heads off the engine causing the coolant to puke oil or fuel into itself and worse, coolant into the oil.
If he's got one with oil/fuel in the coolant, his cause problem is most certainly in the heads, however, the root cause of that problem is a much more difficult animal. It can't be fixed. Without completely reengineering the intake and egr system to put that crap into the exhaust only instead of the intake it will reoccur from now on. That's why Ford went to a new engine after a 3 year experiment with this piece of garbage. The normal cycle on a Ford diesel is 8 to 10 years.
BTW: Both Chevy's Isuzu and Dodge's Cummins went through re-designs as of Jan 1, 2007. Both of then now have a lot of the garbage on them that got Ford into trouble with that 6.0 engine. My best advice would be to find an old 5.9 L Cummins in a Dodge for a replacement. In 07, there were some Dodges made with 5.9's (ones built prior to Jan 1st 07 and a Coal Field Special that is supposedly only sold to mining companies for off road use) I would look for one of these, there are still a very few around new on lots left over, or even used would be better than what you are getting into with what you have.