149,000 miles isn’t too many for the Odyssey engine - they have great engines. The problem with the Odyssey is the transmission. They die early and often. They cost around $4,000 to rebuild. They seem to be better in the 2005 and newer models (the 3rd generation of the Ody.) Is this the original tranny for this Ody, or has it already been rebuilt?
Has the timing belt and water pump been replaced? That could cost $1,000 to do.
Motor mounts also go bad on these and need replacing.