2008 Toyota Prius - Codes and oil consumption

With the 278,000 miles, and the P0420 code I would change the O2 sensor after the CAT
One of the very few O2 sensor codes where replacement would be my first choice, especially with the high mileage.

The P0456 could be as simple as a failing or loose gas cap, again with the age and mileage, I’d just replace it.

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