Toyota Sienna [mini van] 6 cylinder vs. 4 cylinder engine?

The EPA estimates ar 19 cit and 24 highway for the 4 cyl and 18/24 for the 6 cyl. fueleconomy.gov estimates that you will save $143 for every 15,000 miles you drive if gasoline is $3.96 per gallon. That is less than 40 cents per day. The base version with the 6 cyl is $1000 more than the 4-cyl. If you plan to keep it for a long time, it seems to me that the $1000 is not much to pay for the improved road manners of the 6 cyl. The price difference for the LE is more like $3000, and that is a more serious issue.