22Re valve adjustment Cold or Hot?

One other thing I notice on this engine when adjusting the valves, the base circle on the cam seems to vary by a couple of thousands. This is an aftermarket (stock replacement)cam. Engine rebuilt 5,000 miles ago. If valves are adjusted by the Factory Service Manual, you set engine to TDC for cylinder one and then adjust 4 valves, then rotate crank 360 degrees (now set to TDC for cylinder 4) and then adjust remaining 4 valves. So, cylinders 1 and 4 are adjusted when at TDC but 2 and 3 are not. With the varying base circle on the cam it seems like the adjustment from cyliner to cylinder will not be the same. Would it be best to adjust when each cylinder at it’s TDC or adjust each valve when the lobe is opposite the rocker?