I have a 2001 Odyssey which has had three new motor mounts in the last year (between 100,000 and 125,000 miles.) The dealer and local mechanic have indicated that it is a common problem with the Odyssey but have no recommendations for preventing the reoccurance.
I wonder if the problem is not a defect in design but user error. Most of us with Odysseys in my neighborhood spend our time ferrying various numbers (and weights) of children to various afterschool and weekend activities. Speed bumps (of varying degrees of severity) surround all of the venues for children’s activties.
Could it be that Honda simply didn’t anticipate all the torque that 700 lbs of payload (think 6 middle school soccer players and their gear) generate going over multiple speed bumps in and out of a parking lot every day? Add to that the stop and go nature of carpools and seems like a serious misestimation.